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AI Helps Spot Brain Tumor Tissue Surgeons Miss

A newly developed AI program can help doctors detect and potentially remove brain cancer that might otherwise be missed during surgery, a new study demonstrates.

The AI, called FastGlioma, calculated how much residual brain cancer remained following surgery with approximately 92% accuracy, researchers reported Nov. 13 in the journal

  • Dennis Thompson HealthDay Reporter
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  • November 13, 2024
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  • New Hope Against Breast Cancers That Spread to the Brain

    A recently approved targeted chemotherapy drug can significantly extend the lives of advanced breast cancer patients who have developed tumors in their brains, new clinical trial results show.

    On average, patients receiving the drug

  • Dennis Thompson HealthDay Reporter
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  • October 8, 2024
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  • No Link Between Cellphone Use, Brain Cancer, Major Report Finds

    In news that should reassure folks glued to their cellphones all day, a new international review finds no link between cellphone use and brain cancer.

    Commissioned by the World Health Organization (WHO), the review included 11 experts from 10 countries who sifted through decades of research -- 5,000 studies published between 1994 and 2022 to be exact. The final analysis was just publ...

    Childhood Brain Tumor Survivors Can Lag in School -- Interventions Can Help

    Brain tumors in young children are rare, but those who survive them can lag in school for years afterwards, new research shows.

    For those families that can afford it, intervening when kids are still in the preschool years might help them perform better academically later on, researchers said.

    “We now know that we don't need to wait until patients are struggling with math and r...

    Early Trial Shows New Treatment Hits Tough-to-Treat Glioblastomas Harder

    Radioactive substances injected into the body could provide a better way of treating glioblastoma, the most malignant form of brain cancer, a new review says.

    The cancer treatment, called targeted alpha therapy (TAT), involves injection of radioactive alpha particles attached to special molecules that seek out cancer cells in the body.

    Pre-clinical experiments show that TAT increase...

    Why Are Brain Tumors More Deadly for Kids in Poorer Neighborhoods?

    U.S. children with inoperable brain tumors appear to die sooner and find it harder to get care if they live in poorer neighborhoods, a new study finds.

    Children from higher-income areas had more than double the average survival time than kids from poorer neighborhoods -- 480 days versus 235 days, depending if a census tract had an average household income higher or lower than $50,000.

    ...

    Your Head Aches: What Could It Mean, and What Can Be Done About It?

    When there's pain, pressure and pounding in your head, you might think the worst: Is it a brain tumor?

    Probably not, a Penn State physician assures. 

    Headache in and of itself is not a common sign of a tumor, because the brain itself doesn't feel pain, said Dr. John Messmer, medical director at Penn State H...

    Ultrasound Device Delivers Meds to Better Fight Brain Tumors

    One of the biggest obstacles to treating brain cancer is getting tumor-killing drugs past the blood-brain barrier that normally protects the brain from foreign invaders.

    Now, new research shows that ultrasound waves emitted from a device implanted in a cancer patient's skull could be the key to getting chemotherapy and immunotherapy drugs into the brain.

    This ultrasound technology a...

    Doctors May Have Tried to Treat Cancer in Ancient Egypt

    A 4,000-year-old skull provides evidence that ancient Egyptians might have tried to treat cancer, a new study claims.

    Microscopic observation of the skull revealed 30 or so lesions scattered across its surface that are consistent with cancer, researchers report.

    T...

    MRNA Vaccine Fights Deadly Brain Tumor in Small Trial

    An experimental cancer vaccine can quickly reprogram a person's immune system to attack glioblastoma, the most aggressive and lethal form of brain cancer, a small, preliminary study has found.

    The cancer vaccine is based on mRNA technology similar to that used in COVID vaccines, but in this case a patient's own tumor cells are used to create a personalized vaccine, researchers said.

    Hormonal Meds for Birth Control, Menopause Linked to Brain Tumors

    The contraceptive injection Depo-Provera and two drugs used for menopause relief could be linked to a heightened risk for brain tumors in some women, a new study warns.

    Depo-Provera (medroxyprogesterone acetate) increased the risk of intracranial meningioma 5.6-fold if used for longer than a year, researchers report in the BMJ<...

    New Immune-Focused Therapy Shrinks Aggressive Brain Tumors

    Delivering dual-targeted, immune-focused CAR T cancer therapy via a patient's spinal fluid quickly shrank deadly brain tumors, researchers report.

    CAR T therapy harnesses the power of the patient's immune system T-cells, which are reprogrammed to seek and destroy a specific protein found on cancer cells.

    However, in the new trial -- focused on patients with deadly glioblastomas (...

    Brain Cancer Risk Rises in Vets After Serious Head Injury

    People who've suffered a moderate to severe traumatic brain injury have a greatly increased risk of brain cancer, a new study of military service members finds.

    Brain cancer is relatively uncommon, occurring in fewer than 1% of people in the United States, researchers said.

    But service members who had a moderate or severe brain injury were at 90% increased risk for developing malign...

    Rock On: He Played Guitar While Getting His Brain Tumor Removed

    Professional guitarist Christian Nolen took his stage show to an operating room last month, strumming out Deftones tunes for surgeons as they worked to remove a tumor from his brain.

    Nolen's performance wasn't just for entertainment -- his guitar playing helped guide the brain surgeons during the delicate operation.

    By playing the guitar during an "awake"portion of his two-hour surg...

    Cancer Is More Lethal For Black and Hispanic Children: Report

    THURSDAY, Nov. 16, 2023 (Healthday News) -- While childhood cancer is no longer terminal for many, death rates remain higher in Black and Hispanic children, a new government report reveals.

    Treatments for these rare cancers have improved drastically in recent decades, and death rates dropped for all children in 2001 -- and kept dropping for another decade.

    But over the past 10 years...

    Targeted Treatment Shrinks Rare Brain Tumors in Small Study

    A targeted treatment has had unprecedented success in shrinking a rare brain tumor, according to clinical trial results.

    These tumors are papillary craniopharyngiomas (PCPs), and the drug combo is called vemurafenib/cobimetinib.

    Each of 15 patients who received one or more cycles of targeted therapy responded to treatment, with an average 91% reduction in tumor size, Mass Gene...

    AI Tool 'Reads' Brain Tumors During Surgery to Help Guide Decisions

    Scientists have developed an artificial intelligence (AI) tool capable of deciphering a brain tumor's genetic code in real time, during surgery -- an advance they say could speed diagnosis and personalize patients' treatment.

    The researchers trained the AI tool to recognize the different genetic features of gliomas, a group of tumors that constitute the most common form of brain cancer am...

    New Drug Could Be Advance Against Glioma Brain Tumors

    An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.

    The oral drug vorasidenib nearly tripled progression-free survival in patients with grade 2 gliomas compared to placebo, nearly 28 months versus 11 months, according to results presented Sunday at the American Society of Clinical Oncology (ASCO) annual meet...

    Ultrasound Breaches Blood-Brain Barrier, Helping Drugs Fight Tumors

    Brain cancers are notoriously difficult to treat because most chemotherapy drugs can't breach the blood-brain barrier, a microscopic layer of cells that protect the brain from toxins.

    But researchers now say they can temporarily open that barrier and get more chemo to brain tumors, using an experimental ultrasound device.

    The technology led to a four- to sixfold increase in chemo dr...

    In Mouse Study, New Gel Therapy Stops Dangerous Brain Tumors

    A gel applied directly into the brain could offer new hope for patients diagnosed with glioblastoma, the most common malignant brain tumor in adults.

    The gel cured 100% of lab mice with glioblastoma when it was applied to the tumor cavity following surgery to remove the cancer, said senior researcher Honggang Cui,...

    How Many CT Scans Are Safe for Kids?

    Getting a single CT scan during childhood doesn't appear to increase a child's risk of a future brain tumor, leukemia or lymphoma, new research finds, but getting four or more scans more than doubles the chances.

    CT scans use low-dose radiation, which can damage cells. Past evidence about the risks of cancer from these scans in children 18 and younger was conflicting, researchers said.

    CAR-T Therapy Helps Kids Battling Deadly Nervous System Tumors

    A therapy that arms the immune system to find and destroy tumor cells has shown early promise against a rare and aggressive childhood cancer.

    Experts called the findings "promising." But they cautioned that much larger studies are needed to see whether and how the treatment can fit into battling the cancer, called neuroblastoma.

    Neuroblastoma begins in immature nerve cells, with tum...

    Be Aggressive With Initial Brain Tumor Surgery to Boost Survival: Study

    Researchers studying patients with low-grade, slow-growing brain tumors have found that more aggressive surgery may extend survival.

    The trick to treating low-grade gliomas is to remove as much of them as possible soon after diagnosis, researchers at University of California, San Francisco found.

    "Our findings p...

    Race Could Affect Outcomes in Head-and-Neck Cancers

    Black patients with head-and-neck cancers have twice the death rates of white patients, and a new study suggests race itself underlies those differences.

    "What is unique about our study is it strongly supports the conclusion that Black patients seem to respond to therapy differently than white patients,"said study author

  • Cara Murez HealthDay Reporter
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  • December 19, 2022
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  • Black Patients With Brain Tumors Less Likely to Get Surgery Than Whites

    Black patients with brain tumors may be less likely to have surgery recommended to them than white patients are, according to a large U.S. study.

    The research, which looked at two national databases, found that on average, Black patients were less likely to have surgery recommended for any of four types of brain tumor. That included three considered benign (non-cancerous) and one that is ...

    Implant Delivers Chemo Directly to Brain in Patients Battling Brain Tumors

    Researchers have found a way to safely deliver a steady supply of chemotherapy directly to brain tumors -- in what they hope will be an important advance for patients with currently incurable cancers.

    The treatment involves an implantable pump system that supplies a steady drip of chemo straight to the brain tumor. Researchers have tested it in five patients who had recurrent glioblastoma...

    Harnessing a Virus to Fight a Killer Brain Tumor in Kids

    A therapy that uses a virus to kill tumor cells can be safely given to children with a rare, incurable form of brain cancer, an early study has found.

    The study -- published June 30 in the New England Journal of Medicine -- involved just 12 children with the disease, called

  • Amy Norton HealthDay Reporter
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  • June 30, 2022
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  • Weight-Loss Surgery May Greatly Lower Odds for Many Cancers

    Dropping a load of pounds through weight-loss surgery can significantly decrease your risk of developing or dying from cancer, according to three new studies.

    Obese folks who underwent bariatric surgery were at least two times less likely to develop certain types of cancer and more than three times less likely to die of cancer than heavy people who didn't get the procedure, according to a...

    Wildfire Survivors Could Face Higher Cancer Risk

    Wildfires, like the one currently raging in New Mexico, are known to cause upticks in breathing issues and heart attacks in their immediate wake for folks who live nearby.

    Now, new Canadian research shows that these fires may also increase risk for lung and brain cancer o...

    Missed Cancer Screenings During Pandemic Could Raise Death Rate for Years

    The early months of the COVID-19 pandemic kept millions of Americans away from routine cancer screenings. Now a new study finds that many U.S. screening programs were still not back to normal by 2021.

    The study, of more than 700 cancer facilities nationwide, found that in January 2021 - a year after COVID's emergence in the United States - most still had not recovered their pre-pandemic s...

    Half of Americans Live With Legacy of Childhood Lead Poisoning

    If you were born before 1996, there's a good chance you were exposed to high levels of lead as a kid, and new research suggests this may have harmed your IQ and boosted your chances of lead-related health concerns down the road.

    "A significant proportion of Americans alive today had very high lead exposure as children...

    Biden Relaunches Cancer Moonshot Initiative

    President Joe Biden announced Wednesday that he is giving a new push to the cancer moonshot initiative that he first led during the Obama administration.

    In his announcement, Biden said the program would aim to boost prevention, screening and research with a target of reducing the cancer death rate by 50% over the ne...

    New Treatment Greatly Boosts Survival for Kids With Aggressive Brain Cancer

    Children with the rare cancer neuroblastoma often succumb to the disease despite aggressive treatment. But researchers have found that adding an experimental antibody to that treatment, right off the bat, may improve their outlook.

    Of 64 children treated with the antibody in a clinical trial, 74% were still alive and free of a recurrence three years later. That compares with historical ra...

    Tough Choices: Chemo That Can Save Kids With Cancer Can Also Damage Hearing

    The cancer drug cisplatin can save children's lives, but often with the side effect of hearing loss. Now a new study shows that young children are especially vulnerable, and the hearing damage may begin early in the course of treatment.

    The researchers said the findings highlight the need to screen kids' hearing during each round of cisplatin treatment, to catch problems early.

    Fewer American Adults Are Getting Malignant Brain Tumors

    Malignant brain tumor rates are declining among U.S. adults, but patients still have a low chance of survival, a new study finds.

    The researchers also found that rates of noncancerous tumors are on the rise, likely due to increased awareness and improvements in diagnosis.

    "Although the molecular understanding of how brain cancers differ from each other is advancing rapidly, we conti...