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Millions of people undergo joint replacement surgery every year. To prevent infection, doctors often give them a second antibiotic -- but new research suggests this can backfire.

Adding a second antibiotic at the time of hip and knee replacement surgery may actually increase infections, researchers in Australia found.

"Given the number of joint replacements performed in Austral...

Blaming your ailing knees for feeling down?

Unfortunately, even after physical pain eases, healing or fixing an injured joint often does not improve mental health, research shows.

A new study found that anxiety symptoms only improved when a patient had major improvements in physical function.

Depression, meanwhile, did not meaningfully improve even when the improvements to phy...

An anti-inflammatory drug that has been around for over 2,000 years might help delay a very modern problem: hip and knee replacements.

That's the suggestion of a new study finding that older adults who used the drug -- called colchicine -- were less likely to need hip or knee replacement surgery over the next two years, versus those given placebo pills.

The study, published May 30 i...

While joint reconstruction surgeries are fairly common, they may be anything but routine for people with sickle cell disease.

Patients with the blood disorder who undergo total knee replacement are at a higher risk for complications than other patients, according to a new large-scale study.

"SCD patients undergoing total knee replacement need a multidisciplinary approach and ma...

The prices that health insurers agree to pay for joint replacement surgery vary widely and are unrelated to conventional measures of the quality of care.

That's the conclusion of a new study that found who is footing the bill is the biggest influence on the price tag.

Total joint replacements (TJR) -- especially of knees and hips -- are the most common in-hospital surgeries for U.S....

A person doesn't have to pack on very many extra pounds before their risk of needing a knee replacement increases substantially, a new evidence review has found.

Weight gain of just 11 pounds increases a woman's odds of needing total knee replacement surgery by one-third, and a man's by one-quarter, researchers rep...

Losing excess weight may not only help prevent knee arthritis, but also slow its progression in people who already have the condition, a recent study suggests.

Researchers found that among over 9,000 middle-aged and older adults, those who managed to shed some extra weight benefited their knees in two ways...

Researchers may have found a new way to help ease the pain of knee replacement surgery: infusing morphine directly into the shin bone.

The findings come from a recent study of 48 patients undergoing